Lutetium-177, plus ipilimumab and nivolumab

The trial is called EVOLUTION.

This trial is adding to Lutetium-177 treatment, two immunotherapy drugs - the checkpoint inhibitors ipilimumab and nivolumab.

Immune checkpoints are key regulators of the immune system

Yervoy (ipilimumab) blocks checkpoint CTLA-4

Opdivo (nivolumab) and Keytruda (pembrolizumab) block checkpoint CD-1

Now mostly used for melanoma and lung cancer.

As you can see from the Contacts on the bible of clinical trials it is being offered in many hospitals around Australia.

It is being organised by the cross-Tasman research organisation ANZUP

1 view0 comments

Recent Posts

See All

In short: Medicare (Australia) will pay for one PSMA scan after diagnosis, before you have any treatment, if you are intermediate risk or high risk. Medicare will pay for two PSMA scans after your fir

A PSMA PET/CT scan can detect prostate cancer at very low levels. Indeed, when PSMA first became available, and not much was known about it, my doctor ordered the scan 'just to see what it shows' and